Introduction to pathophysiology concepts
Homeostasis and adaptive responces to stressors
Cell structure and function
Cell injury, aging, and death
Molecular genetics and tissue differentiation
Genetic and developmental disorders
Neoplasia
Infectious processes
Inflammation and immunity
Alternations in immune function
Malignant disorders of white blood cells
HIV disease and AIDS
Alterations in oxygen transport
Alterations in hemostasis and blood coagulation
Alterations in blood flow
Alterations in blood pressure
Cardiac function
Alterations in cardiac function
Heart failure and dysrhythmias: common sequelae of cardiac diseases
Shock
Respiratory function and alterations in gas exchange
Obstructive pulmonary disorders
Restrictive pulmonary disorders
Fluid and electrolyte homeostasis and imbalances
Acid-base homeostasis and imbalances
Renal function
Intrarenal disorders
Acute renal failure and chronic kidney disease
Disorders of the lower urinary tract
Male genital and reproductive function
Alterations in male genital and reproductive function
Female genital and reproductive function
Alterations in female genital and reproductive function
Sexually transmitted infections
Gastrointestinal function
Gastrointestinal disorders
Alterations in function of the gallbladder and exocrine pancreas
Liver diseases
Endocrine physiology and mechanisms of hypothalamic-pituitary regulation
Disorders of endocrine function
Diabetes mellitus
Alterations in metabolism and nutrition
Structure and function of the nervous system
Acute disorders of brain function
Chronic disorders of neurologic function
Alterations in special sensory function
Pain
Neurobiology of psychotic illnesses
Neurobiology of nonpsychotic illnesses
Structure and function of the musculoskeletal system
Alterations in musculoskeletal function: trauma, infection, and disease
Alterations in musculoskeletal function: rheumatic disorders
Alterations in the integumentary system
Burn injuries

With dynamic full-color illustrations and an easy-to-read writing style, this 4th Edition explores the etiology, pathogenesis, clinical manifestation, and treatment of disease. Each unit covers a specific body system and begins with an illustrated review of anatomy and normal physiology to prepare you for disease processes and abnormalities discussions. Coverage of the latest developments in pathophysiology and a wealth of student-friendly learning resources will help you understand all of the major degenerative, neoplastic, metabolic, immunologic and infectious diseases. Highlighted Key Points focus you on the most important information. Additional content on the Companion CD and the companion Evolve website provide more opportunities for learning with case study worksheets, additional exercises, animations, and much more. Revised content includes the most current information and research on RNA molecules in cell function, guidelines, heart failure, alzheimers, and more to keep you at the cutting-edge of pathophysiology. A new focus on general introductory principles and data measurement in clinical practice provides a solid beginning to pathophysiology study