Abeloff's clinical oncology /
John E. Niederhuber ; [edited by] James O. Armitage, James H. Doroshow, Michael B. Kastan.
- Sixth edition.
- XXXIII-2037 p. : illustration.
Includes index
Part I: Science and clincial oncology. Section A: Biology and cancer. Molecular tools in cancer research Intracellular signaling The cellular microenvironment and metastases Control of the cell cycle The pathophysiology of cancer cell death Cancer immunology Stem cells, cell differentiation, and cancer Vascular and interstitial biology of tumors Cancer metabolism Section B: Genesis of cancer. Environmental factors DNA damage response pathways and cancer Viruses and human cancer Genetic factors: hereditary cancer predisposition syndromes Genetic and epigenetic changes in cancer Section C: Diagnosis of cancer. Pathology, biomarkers, and molecular diagnostics Imaging Section D: Clinical trials. Biostatistics and bioinformatics in clinical trials Trial design Structures supporting cancer clinical trials Oncology and health care policy Section E: Prevention and early detection. Discovery and characterization of cancer genetic susceptibility alleles Lifestyle and cancer prevention Cancer screening and early detection Nicotine dependence: current treatments and future directions Section F: Treatment. Cancer pharmacology Therapeutic targeting of cancer cells: era of molecularly targeted agents Basics of radiation therapy Hematopoietic stem cell transplantation Gene therapy in oncology Therapeutic antibodies and immunologic conjugates Complementary and alternative medicine Part II: Problems common to cancer and therapy Section A: Hematologic problems and infections. Disorders of blood cell production in clinical oncology Diagnosis, treatment, and prevention of cancer-related venous thrombosis Infection in the patient with cancer Section B: Symptom management. Hypercalcemia Tumor lysis syndrome Cancer-related pain Cancer cachexia Nausea and vomiting Section C: Treatment complications. Oral complications Dermatologic toxicities of anticancer therapy Cardiovascular effects of cancer therapy Reproductive complications Paraneoplastic neurologic syndromes Neurologic complications Endocrine complications Pulmonary complications of anticancer treatment Section D: post treatment considerations. Rehabilitation of individuals with cancer Survivorship Second malignant neoplasms Caring for patients at the end of life Section E: Local effects of cancer and its metastasis. Acute abdomen, bowel obstruction, and fistula Superior vena cava syndrome Spinal cord compression Brain metastases and neoplastic meningitis Bone metastases Lung metastases Liver metastases Malignancy-related effusions Section F: Special populations. Cancer in the elderly: biology, prevention, and treatment Special issues in pregnancy Human immunodeficiency virus (HIV) infection and cancer Part III: Specific malignancies. Section A: Central nervous system. Cancer of the central nervous system Section B: Head, neck, and eye. Ocular tumors Cancer of the head and neck Section C: Skin. Melanoma Nonmelanoma skin cancers: basal cell and squamous cell carcinomas Section D: Endocrine. Cancer of the endocrine system Section E: Thoracic. Cancer of the lung: non-small cell lung cancer and small cell lung cancer Diseases of the pleura and mediastinum Cancer of the esophagus and gastroesophageal junction Section F: Gastrointestinal. Cancer of the stomach and gastroesophageal junction Cancer of the small bowel Colon cancer Cancer of the rectum Cancer of the anal canal Liver and bile duct cancer Carcinoma of the pancreas Section G: Genitourinary. Cancer of the kidney Carcinoma of the bladder Prostate cancer Cancer of the penis Testicular cancer Section H: Gynecological. Cancers of the cervix, vulva, and vagina Cancer of the endometrium Ovaries and fallopian tubes Gestational trophoblastic disease Cancer of the breast Section I: Sarcomas. Sarcomas of bone Sarcomas of soft tissue Section J: Cancer of undefined site of origin. Carcinoma of Unknown Primary Section K: Pediatrics. Pediatric solid tumors Childhood leukemia Childhood lymphoma Section L: Hematological. Acute leukemias in adults Myelodysplastic syndromes Myeloproliferative disorders Chronic myeloid leukemia Chronic lymphoid leukemias Hairy cell leukemia Multiple myeloma and related disorders Hodgkin's Lymphoma Non-Hodgkin lymphoma Cutaneous T-cell lymphoma and cutaneous B-cell lymphoma Adult T-cell leukemia-lymphoma
Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up"--Publisher's description