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Hematology: basic principles and practice / Ronald Hoffman (Editor), Edward J. Benz (Editor), Leslie E. Silberstein (Editor), Helen Heslop (Editor), Jeffrey I. Weitz (Editor), John Anastasi (Editor), Mohamed E. Salama (Editor), Syed A. Abutalib (Editor)

By: Contributor(s): Philadelphia, PA: Elsevier, 2018Edition: Seventh editionDescription: 1 online resource (xxx, 2374 pages) : illustrations (chiefly color)Content type:
  • txt
Media type:
  • n
Carrier type:
  • nc
ISBN:
  • 9780323357623
Subject(s): LOC classification:
  • RC633 .HEM 2018
Contents:
Anatomy and physiology of the gene Epigenetics and epigenomics Genomic approaches to hematology Regulation of gene expression, transcription, splicing and RNA metabolism Protein synthesis, processing, and trafficking Protein architecture: relationship of form and function Signaling transduction and metabolomics Pharmacogenomics and hematologic diseases Hematopoietic stem cell biology Stem cell model of hematologic malignancies Hematopoietic microenvironment Cell adhesion Hematopoietic cell trafficking and chemokines Interactions between hematopoietic stem and progenitor cells and the bone marrow: current biology of stem cell homing and mobilization Vascular growth in health and disease Cytokine/receptor families and signal transduction Control of cell division Cell death Overview and compartmentalization of the immune system B-cell development T-cell immunity Natural killer cell immunity Dendritic cell biology Complement and immunoglobulin biology leading to clinical translation Tolerance and autoimmunity Biology of erythropoiesis, erythroid differentiation, and maturation Granulocytopiesis and monocytopoiesis Thrombocytopoiesis Inherited forms of bone marrow failure Aplastic anemia Paroxysmal nocturnal hemoglobinuria Acquired disorders of unilineage blood cell production Pathobiology of the human erythrocyte and its hemoglobins Approach to anemia in the adult and child Pathophysiology of iron homeostasis Disorders of iron metabolism: iron deficiency and overload Anemia of chronic diseases Heme biosynthesis and its disorders: porphyrias and sideroblastic anemias Megaloblastic anemias Thalassemia syndromes Pathobiology of sickle cell disease Sickle cell disease: clinical features and management Hemoglobin variants associated with hemolytic anemia, altered oxygen affinity, and methemoglobinemias Red blood cell enzymopathies Red blood cell membrane disorders Autoimmune hemolytic anemia Extrinsic nonimmune hemolytic anemias Granulocytosis, granulocytopenia, monocytosis, and monocytopenia Lymphocytosis, lymphocytopenia, hypergammaglobulinemia, and hypogammaglobulinemia Disorders of phagocyte function Congenital disorders of lymphocyte function Histiocytic disorders Lysosomal storage diseases: perspectives and principles Infectious mononucleosis and other Epstein-Barr virus-associated diseases Progress in the classification of hematopoietic and lymphoid neoplasms: clinical implications The cytogenomic basis of hematological malignancies Pharmacology and molecular mechanisms of antineoplastic agents for hematologic malignancies Pathobiology of acute myeloid leukemia Clinical manifestations and treatment of acute myeloid leukemia Myelodysplastic syndromes: biology and treatment Allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndrome in adults Acute myeloid leukemia in children Myelodysplastic syndrome and myeloproliferative syndrome in children Pathobiology of acute lymphoblastic leukemia Clinical manifestations and treatment in children of acute lymphoblastic leukemia Acute lymphocytic leukemia in adults Chronic myeloid leukemia The polycythemias Essential thrombocythemia Primary myelofibrosis Eosinophilia, eosinophil-associated diseases, chronic eosinophil leukemia, and the hypereosinophilic syndromes Mast cells and systemic mastocytosis The pathologic basis for the classification of non-Hodgkin and Hodgkin lymphomas Origins of Hodgkin disease Hodgkin lymphoma: clinical manifestations, staging, and therapy Origins of non-Hodgkin lymphomas Chronic lymphocytic leukemia Hairy cell leukemia Clinical manifestations and treatment of indolent lymphomas: marginal zone lymphomas (extranodal/malt, splenic, and nodal) Clinical manifestations, staging, and treatment of follicular lymphoma Mantle cell lymphoma Diagnosis and treatment of diffuse large b-cell lymphoma (DLBCL) and Burkitt lymphoma (BL) Viral-related lymphomas Malignant lymphomas in childhood T-cell lymphomas Multiple myeloma Waldenstrom macroglobulinemia/lymphoplasmacytic lymphoma Immunoglobuin light-chain amyloidosis (primary amyloidosis) Clinical approach to infections in the compromised host Psychosocial aspects of hematologic disorders Pain management and antiemetic therapy in hematologic disorders Palliative care Late complications of hematologic diseases and their therapies Overview and historical perspective of current cell-based therapies Practical aspects of hematologic stem cell harvesting and mobilization IND enabling processes for cell-based therapies Graft engineering and cell processing Principles of cell-based genetic therapies Mesenchymal stromal cells T cell therapy of hematological diseases NK cell-based therapies Immune checkpoint blockade in hematologic malignancies Overview and choice of donor of hematopoietic stem cell transplantation Indications and outcomes of allogeneic hematopoietic cell transplantation for hematologic malignancies in adults Unrelated donor hematopoietic cell transplantation Haploidentical hematopoietic cell transplantation Unrelated donor cord blood transplantation for hematologic malignancies Graft-versus-host disease and graft-versus-leukemia responses: biology and therapy Complications after hematopoietic cell transplantation Human blood group antigens and antibodies Principles of red blood cell transfusion Clinical considerations in platelet transfusion therapy Human leukocyte antigen and human neutrophil antigen systems Principles of neutrophil (granulocyte) transfusions Transfusion of plasma derivatives: plasma, cryoprecipitate, albumin, and immunoglobulins Preparation of plasma-derived and recombinant human plasma proteins Transfusion therapy for coagulation factor deficiencies Hemapheresis Transfusion reactions to blood and cell therapy products Transfusion-transmitted diseases Pediatric transfusion medicine Overview of hemostasis and thrombosis The blood vessel wall Megakaryocyte and platelet structure Molecular basis of platelet function Molecular basis of blood coagulation Regulatory mechanisms in hemostasis Clinical approach to the patient with bleeding or bruising Laboratory evaluation of hemostatic and thrombotic disorders Acquired disorders of platelet function Diseases of platelet number: immune thrombocytopenia, neonatal alloimmune thrombocytopenia, and posttransfusion purpura Thrombocytopenia caused by platelet destruction, hypersplenism, or hemodilution Heparin-induced thrombocytopenia Thrombotic thrombocytopenic purpura and the hemolytic uremic syndromes Hemophilia A and B Inhibitors in hemophilia A and B Rare coagulation factor deficiencies Structure, biology, and genetics of von Willebrand factor Disseminated intravascular coagulation Hypercoagulable states The antiphospholipid syndrome Venous thromboembolism Mechanical interventions in arterial and venous thrombosis Atherothrombosis Stroke Acute coronary syndromes Atrial fibrillation Peripheral artery disease Antithrombotic drugs Disorders of coagulation in the neonate Hematologic changes of pregnancy Hematologic manifestations of childhood illness Hematologic manifestations of systemic disease: liver disease Hematologic manifestations of systemic disease: renal disease Hematologic manifestations of cancer Integrated therapies in patients with hematologic diseases Hematologic manifestations of aids Hematologic manifestations of parasitic diseases Hematologic problems in the surgical patient: bleeding and thrombosis The spleen and its disorders Hematology in aging
Summary: Get the expert guidance you need to offer your patients the best possible outcomes with Hematology: Basic Principles and Practice, 7th Edition. This thoroughly up-to-date text contains both unparalleled scientific content and must-know clinical guidance, so you can enhance your problem-solving skills and make optimal use of the newest diagnostic techniques and therapeutic options in this fast-changing field"
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Holdings
Item type Current library Home library Collection Call number Copy number Status Date due Barcode Item holds
Books Books Medical Library General Stacks Medical Library Non-fiction RC633. HEM 2018 (Browse shelf(Opens below)) c.1 Available 033004
Total holds: 0

Revised edition of: Hematology : basic principles and practice / [edited by] Ronald Hoffman [and others]. 6th ed. ♭2013

Includes index

Anatomy and physiology of the gene
Epigenetics and epigenomics
Genomic approaches to hematology
Regulation of gene expression, transcription, splicing and RNA metabolism
Protein synthesis, processing, and trafficking
Protein architecture: relationship of form and function
Signaling transduction and metabolomics
Pharmacogenomics and hematologic diseases
Hematopoietic stem cell biology
Stem cell model of hematologic malignancies
Hematopoietic microenvironment
Cell adhesion
Hematopoietic cell trafficking and chemokines
Interactions between hematopoietic stem and progenitor cells and the bone marrow: current biology of stem cell homing and mobilization
Vascular growth in health and disease
Cytokine/receptor families and signal transduction
Control of cell division
Cell death
Overview and compartmentalization of the immune system
B-cell development
T-cell immunity
Natural killer cell immunity
Dendritic cell biology
Complement and immunoglobulin biology leading to clinical translation
Tolerance and autoimmunity
Biology of erythropoiesis, erythroid differentiation, and maturation
Granulocytopiesis and monocytopoiesis
Thrombocytopoiesis
Inherited forms of bone marrow failure
Aplastic anemia
Paroxysmal nocturnal hemoglobinuria
Acquired disorders of unilineage blood cell production
Pathobiology of the human erythrocyte and its hemoglobins
Approach to anemia in the adult and child
Pathophysiology of iron homeostasis
Disorders of iron metabolism: iron deficiency and overload
Anemia of chronic diseases
Heme biosynthesis and its disorders: porphyrias and sideroblastic anemias
Megaloblastic anemias
Thalassemia syndromes
Pathobiology of sickle cell disease
Sickle cell disease: clinical features and management
Hemoglobin variants associated with hemolytic anemia, altered oxygen affinity, and methemoglobinemias
Red blood cell enzymopathies
Red blood cell membrane disorders
Autoimmune hemolytic anemia
Extrinsic nonimmune hemolytic anemias
Granulocytosis, granulocytopenia, monocytosis, and monocytopenia
Lymphocytosis, lymphocytopenia, hypergammaglobulinemia, and hypogammaglobulinemia
Disorders of phagocyte function
Congenital disorders of lymphocyte function
Histiocytic disorders
Lysosomal storage diseases: perspectives and principles
Infectious mononucleosis and other Epstein-Barr virus-associated diseases
Progress in the classification of hematopoietic and lymphoid neoplasms: clinical implications
The cytogenomic basis of hematological malignancies
Pharmacology and molecular mechanisms of antineoplastic agents for hematologic malignancies
Pathobiology of acute myeloid leukemia
Clinical manifestations and treatment of acute myeloid leukemia
Myelodysplastic syndromes: biology and treatment
Allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndrome in adults
Acute myeloid leukemia in children
Myelodysplastic syndrome and myeloproliferative syndrome in children
Pathobiology of acute lymphoblastic leukemia
Clinical manifestations and treatment in children of acute lymphoblastic leukemia
Acute lymphocytic leukemia in adults
Chronic myeloid leukemia
The polycythemias
Essential thrombocythemia
Primary myelofibrosis
Eosinophilia, eosinophil-associated diseases, chronic eosinophil leukemia, and the hypereosinophilic syndromes
Mast cells and systemic mastocytosis
The pathologic basis for the classification of non-Hodgkin and Hodgkin lymphomas
Origins of Hodgkin disease
Hodgkin lymphoma: clinical manifestations, staging, and therapy
Origins of non-Hodgkin lymphomas
Chronic lymphocytic leukemia
Hairy cell leukemia
Clinical manifestations and treatment of indolent lymphomas: marginal zone lymphomas (extranodal/malt, splenic, and nodal)
Clinical manifestations, staging, and treatment of follicular lymphoma
Mantle cell lymphoma
Diagnosis and treatment of diffuse large b-cell lymphoma (DLBCL) and Burkitt lymphoma (BL)
Viral-related lymphomas Malignant lymphomas in childhood
T-cell lymphomas
Multiple myeloma
Waldenstrom macroglobulinemia/lymphoplasmacytic lymphoma
Immunoglobuin light-chain amyloidosis (primary amyloidosis)
Clinical approach to infections in the compromised host
Psychosocial aspects of hematologic disorders
Pain management and antiemetic therapy in hematologic disorders
Palliative care
Late complications of hematologic diseases and their therapies
Overview and historical perspective of current cell-based therapies
Practical aspects of hematologic stem cell harvesting and mobilization
IND enabling processes for cell-based therapies
Graft engineering and cell processing
Principles of cell-based genetic therapies
Mesenchymal stromal cells
T cell therapy of hematological diseases
NK cell-based therapies
Immune checkpoint blockade in hematologic malignancies
Overview and choice of donor of hematopoietic stem cell transplantation
Indications and outcomes of allogeneic hematopoietic cell transplantation for hematologic malignancies in adults
Unrelated donor hematopoietic cell transplantation
Haploidentical hematopoietic cell transplantation
Unrelated donor cord blood transplantation for hematologic malignancies
Graft-versus-host disease and graft-versus-leukemia responses: biology and therapy
Complications after hematopoietic cell transplantation
Human blood group antigens and antibodies
Principles of red blood cell transfusion
Clinical considerations in platelet transfusion therapy
Human leukocyte antigen and human neutrophil antigen systems
Principles of neutrophil (granulocyte) transfusions
Transfusion of plasma derivatives: plasma, cryoprecipitate, albumin, and immunoglobulins
Preparation of plasma-derived and recombinant human plasma proteins
Transfusion therapy for coagulation factor deficiencies
Hemapheresis
Transfusion reactions to blood and cell therapy products
Transfusion-transmitted diseases
Pediatric transfusion medicine
Overview of hemostasis and thrombosis
The blood vessel wall
Megakaryocyte and platelet structure
Molecular basis of platelet function
Molecular basis of blood coagulation
Regulatory mechanisms in hemostasis
Clinical approach to the patient with bleeding or bruising
Laboratory evaluation of hemostatic and thrombotic disorders
Acquired disorders of platelet function
Diseases of platelet number: immune thrombocytopenia, neonatal alloimmune thrombocytopenia, and posttransfusion purpura
Thrombocytopenia caused by platelet destruction, hypersplenism, or hemodilution
Heparin-induced thrombocytopenia
Thrombotic thrombocytopenic purpura and the hemolytic uremic syndromes
Hemophilia A and B
Inhibitors in hemophilia A and B
Rare coagulation factor deficiencies
Structure, biology, and genetics of von Willebrand factor
Disseminated intravascular coagulation
Hypercoagulable states
The antiphospholipid syndrome
Venous thromboembolism
Mechanical interventions in arterial and venous thrombosis
Atherothrombosis
Stroke
Acute coronary syndromes
Atrial fibrillation
Peripheral artery disease
Antithrombotic drugs
Disorders of coagulation in the neonate
Hematologic changes of pregnancy
Hematologic manifestations of childhood illness
Hematologic manifestations of systemic disease: liver disease
Hematologic manifestations of systemic disease: renal disease
Hematologic manifestations of cancer
Integrated therapies in patients with hematologic diseases
Hematologic manifestations of aids
Hematologic manifestations of parasitic diseases
Hematologic problems in the surgical patient: bleeding and thrombosis
The spleen and its disorders
Hematology in aging

Get the expert guidance you need to offer your patients the best possible outcomes with Hematology: Basic Principles and Practice, 7th Edition. This thoroughly up-to-date text contains both unparalleled scientific content and must-know clinical guidance, so you can enhance your problem-solving skills and make optimal use of the newest diagnostic techniques and therapeutic options in this fast-changing field"

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