MARC details
| 000 -LEADER |
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| fixed length control field |
05805cam a22003494a 4500 |
| 001 - CONTROL NUMBER |
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| control field |
14079824 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
GZU |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20221007101534.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
050819s2006 maua b 001 0 eng |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
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| LC control number |
2005024163 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
0120885433 (alk. paper) |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0120885433 |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(OCoLC)ocm61451512 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
DLC |
| Transcribing agency |
DLC |
| Modifying agency |
YDX |
| -- |
BAKER |
| -- |
CUX |
| -- |
DLC |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QP624.5. |
| Item number |
MUL 2006 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Müller, Hans-Joachim. |
| Relator term |
author |
| 245 10 - TITLE STATEMENT |
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| Title |
Microarrays / |
| Statement of responsibility, etc. |
Hans-Joachim Müller, Thomas Röder . |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Burlington, MA : |
| Name of publisher, distributor, etc. |
Elsevier Academic Press, |
| Date of publication, distribution, etc. |
c2006. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xv, 212 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
26 cm. |
| 440 #4 - SERIES STATEMENT/ADDED ENTRY--TITLE |
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| Title |
The experimenter series |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes bibliographical references (p. 201) and index. |
| 505 ## - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Acknowledgment v <br/>Foreword xi <br/>Abbreviations xiii <br/>Introduction<br/>1 (6)<br/>Terminology<br/>2 (1)<br/>Design and development of microarrays<br/>3 (4)<br/>Applications<br/>7 (8)<br/>Scientific problems<br/>7 (3)<br/>The pharmaceutical goal<br/>10 (2)<br/>The demands of biotechnical companies<br/>12 (3)<br/>Technology<br/>15 (90)<br/>Protein microarrays<br/>15 (42)<br/>Gene and protein expression<br/>15 (9)<br/>Protein sundries: from molecule to biochip<br/>24 (18)<br/>Protein chips<br/>42 (15)<br/>Nucleic and microarrays<br/>57 (19)<br/>Hybridization probes<br/>57 (6)<br/>Minimal quantities of RNA-7; What to do?<br/>63 (7)<br/>Production of DNA microarrays<br/>70 (6)<br/>Microarray detection<br/>76 (18)<br/>Light and radiation<br/>76 (2)<br/>Luminescent fluorophore T<br/>78 (6)<br/>High-energy laser light<br/>84 (2)<br/>Microarray scanner: Mode of operation<br/>86 (4)<br/>Operating mode of microarray imagers<br/>90 (2)<br/>Dynamic range<br/>92 (1)<br/>Pixels and spots<br/>93 (1)<br/>Microarray marking systems<br/>94 (11)<br/>Tyramide-signal amplification<br/>94 (1)<br/>Dendrimers....<br/>95 (1)<br/>Quantum dots<br/>96 (3)<br/>Chemiluminescence<br/>99 (1)<br/>Radioactivity<br/>100 (1)<br/>Time-resolved fluorescence<br/>100 (5)<br/>Instrumentation and Software<br/>105 (36)<br/>Microarray spotters<br/>106 (9)<br/>Mechanical contact spotting<br/>110 (1)<br/>Piezo-dispenser technology<br/>111 (4)<br/>Grids and spots<br/>115 (1)<br/>Digitizing: The microarray scanner<br/>115 (2)<br/>The microarray imager<br/>116 (1)<br/>The microarray scanner<br/>117 (1)<br/>Microarray software and documentation<br/>117 (19)<br/>Documentation of microarray experiments<br/>119 (1)<br/>Design of the experiment<br/>120 (1)<br/>Validation of the results<br/>121 (2)<br/>Microarray software<br/>123 (6)<br/>Comparison of expression data<br/>129 (2)<br/>Advanced analysis<br/>131 (5)<br/>Additional laboratory equipment and Laboratory requirements for microarray applications<br/>136 (1)<br/>Supplies<br/>136 (1)<br/>Additional helpful laboratory equipment<br/>136 (1)<br/>Clean-room technology<br/>137 (4)<br/>Cleanliness classes<br/>137 (1)<br/>Clean-room systems<br/>138 (3)<br/>Execution of the Microarray Experiment<br/>141 (14)<br/>Isolation and preparation of nucleic acids<br/>141 (8)<br/>Isolation of RNA ......<br/>141 (1)<br/>mRNA isolation from eukaryotes<br/>142 (1)<br/>mRNA isolation from bacteria<br/>142 (1)<br/>Specimen fabrication with the aid of cDNA synthesis<br/>143 (1)<br/>Hybridization on the DNA biochip<br/>144 (1)<br/>Preamplification with T7-RNA polymerase<br/>144 (2)<br/>Fabrication of the microarray samples<br/>146 (1)<br/>Quantification, inspection, reliability<br/>147 (1)<br/>Hybridization of the samples<br/>147 (2)<br/>Poly (L-lysine) coating<br/>149 (1)<br/>Protein array protocols<br/>149 (6)<br/>Protein array buffers<br/>150 (2)<br/>Verification with antibodies<br/>152 (1)<br/>Protein kinase array: Verification with 33P<br/>153 (2)<br/>High-Throughput Screening<br/>155 (14)<br/>Laboratory automation<br/>156 (8)<br/>Laboratory automation software<br/>158 (2)<br/>Preparation of samples<br/>160 (1)<br/>Analysis and reporting<br/>160 (4)<br/>Drug-target screening<br/>164 (1)<br/>Clinical chemistry and genetic screening<br/>164 (5)<br/>Database Research and Patents<br/>169 (16)<br/>Database research<br/>169 (1)<br/>Patents<br/>170 (13)<br/>Patent research<br/>171 (6)<br/>Patent-protected technologies<br/>177 (6)<br/>Brands and trademarks<br/>183 (2)<br/>Prospects for the Future<br/>185 (6)<br/>Technical developments<br/>185 (1)<br/>Requirement profiles<br/>186 (3)<br/>The end of the end<br/>189 (2)<br/>Appendix<br/>191 (6)<br/>Common buffers<br/>191 (1)<br/>Spotting- and washing buffers<br/>191 (1)<br/>Block solutions<br/>191 (1)<br/>Hybridization solutions<br/>192 (1)<br/>Formula for the calculation of the annealing temperature of oligonucleotides<br/>192 (1)<br/>Formula for oligonucleotides up to 15 bases<br/>192 (1)<br/>Formula for oligonucleotides from 20 to 70 bases<br/>192 (1)<br/>Molar specifications and calculations<br/>192 (2)<br/>Definition of a mole<br/>192 (1)<br/>Definition of molar mass and molarity<br/>192 (1)<br/>Picomolar quantities for nucleic acids<br/>193 (1)<br/>Definition of the dalton unit<br/>193 (1)<br/>Picomolar quantities for proteins and peptides<br/>194 (1)<br/>Calculation of the microarray spot surface area<br/>194 (1)<br/>Calculation of the microarray spot density<br/>195 (1)<br/>Spot density based on center-to-center distance<br/>195 (1)<br/>Spot density based on the number of absolute spots per cm2<br/>195 (1)<br/>Calculation of fluorophore or target density<br/>195 (2)<br/>Company Register 197 (4)<br/>Web Links 201 (2)<br/>Index 203 <br/> |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Microarray technology allows us to answer many questions about gene expression and drug-target screening by employing high-throughput screening. This book dedicates itself to microarrays with clear and understandable explanations and an overview of the presently available hardware, biochips and software. Separate chapters cover the different requirements for DNA and protein chips as well as spotters and scanners |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
DNA microarrays. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Oligonucleotide Array Sequence Analysis |
| General subdivision |
methods. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Gene Expression Profiling |
| General subdivision |
instrumentation. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Röder, Thomas. |
| Relator term |
author |
| 856 41 - ELECTRONIC LOCATION AND ACCESS |
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| Materials specified |
Table of contents only |
| Uniform Resource Identifier |
<a href="http://www.loc.gov/catdir/toc/ecip0518/2005024163.html">http://www.loc.gov/catdir/toc/ecip0518/2005024163.html</a> |
| 856 42 - ELECTRONIC LOCATION AND ACCESS |
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| Materials specified |
Publisher description |
| Uniform Resource Identifier |
<a href="http://www.loc.gov/catdir/enhancements/fy0661/2005024163-d.html">http://www.loc.gov/catdir/enhancements/fy0661/2005024163-d.html</a> |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
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7 |
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cbc |
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orignew |
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1 |
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ecip |
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20 |
| g |
y-gencatlg |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Books |
| Classification part |
624.5 |
| Item part |
MUL |
| Call number prefix |
QP |
